Evaluation of Glycemic Status and Lipid Profile among Patients Attending a Tertiary Care Centre: A Laboratory-Based Observational Study
Keywords:
Glycemic status; Dyslipidemia; Fasting plasma glucose; Lipid profile; Prediabetes; Diabetes mellitus; Cardiometabolic riskAbstract
Background: Disturbances in glucose metabolism are frequently accompanied by abnormalities in lipid metabolism, increasing the risk of atherosclerotic cardiovascular disease. Simultaneous assessment of glycemic status and lipid profile may help identify patients with increased cardiometabolic risk at an early stage. This study evaluated glycemic status and lipid profile among patients attending a tertiary care centre.
Methods: This retrospective observational laboratory-based study was conducted in the Department of Biochemistry, Father Colombo Institute of Medical Sciences, Warangal, Telangana, India, over nine months from January to September 2024. Laboratory records of 300 adult patients with complete fasting plasma glucose and lipid profile results were analysed.
Results: Of the 300 patients, 92 (30.7%) had normal glycemic status, 86 (28.7%) were prediabetic, and 122 (40.7%) were in the diabetic range. Mean total cholesterol, triglycerides, and LDL-C progressively increased across normal, prediabetic, and diabetic groups, whereas mean HDL-C decreased significantly (all p<0.001).
Conclusion: Worsening glycemic status was strongly associated with an increasingly adverse lipid profile.
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